Developments of DNA profiles Essay Example | Topics and Well Written Essays - 2250 words

Developments of DNA profiles - Essay Example g of the PCR primers are efficient and reliable forensic DNA analysis techniques as there is a inverse correlation between the number of polymorphic loci examined and the probability of identical alleles in two individuals. Developing DNA profiles for the identification of individuals who are unknown or identifiable or victims of accidents, calamities, crimes, and disasters using automated STR multiplex kits that rely on spectral resolution using different colored fluorescent dyes to label the overlapping loci due the presence of alleles that fall in the same size range has proven to be one of the most innovative methods. In fact, the polyacrylamide gels that are used in STR can resolve DNA fragments that differ by as little as 1 nucleotide in length and this precise allele designation eliminates the need for match guidelines and continuous allele distribution models that are usually needed in conventional DNA profiling methods The genes are the smaller portions of the DNA that produce a particular product, such as protein. They are particularly useful in the process for profiling. Other portions of the DNA whose functions are not determined yet are called â€Å"spacer or packer DNA between the genes† (DNA Profiling n.d., p. 2). These areas are called minisatellites while the smaller repetitive sequences are called as microsatellites (e.g. 4 base pairs). Short Tandem Repeats or STRs determine the number of times the sequence is repeated. Though identification is prohibitive in developing countries where the technology is quite expensive due to extensive processing, these countries usually send DNA samples to developed countries for analysis and profiling. (Lehman & Criscuolo 2009, p. 1). The Short Tandem Repeat or STR process of identification is said to be the new methodology is DNA profiling (DNA Profiling n.d., p. 3). The STR loci are said to be the â€Å"informative genetic markers† for DNA profiling currently in use, even for the degraded samples (Budowlea,